Binciken masana kimiyya na Ostiraliya ya tabbatar da cewa NMN na iya ƙarfafa ƙasusuwa

Yayin da muke tsufa, ƙasusuwanmu suna yin rauni kuma suna iya samun karyewa, kuma maganin da ake yi a yanzu zai iya ƙara yawan ƙashi kaɗan ne kawai. Wannan matsalar ta taso ne a mafi yawan lokuta saboda ba a san ainihin abin da ke haifar da osteoporosis ba (rage yawan ƙashi da yawa).

Kwanan nan, masu bincike na Ostiraliya sun buga sakamakon binciken kimiyya a cikin Mujallar Gerontology: Jerin A: NMN na iya rage tsufan ƙwayoyin ƙashi na ɗan adam da kuma haɓaka warkar da ƙashi a cikin beraye masu fama da osteoporosis. "Binciken ya nuna NMN a matsayin ingantaccen kuma mai yiwuwa ga mai fama da osteoporosis don hana osteoporosis da haɓaka warkar da ƙashi ga tsofaffi masu fama da osteoporosis," in ji marubutan.

一,NMNyana haɓaka sake farfaɗowar osteoblasts kuma yana ƙara girman ƙashi

Kamar sauran gabobin jikin ɗan adam, ƙasusuwa suna da ƙwayoyin halitta masu rai. Saboda haka, tsofaffin ƙasusuwa da suka lalace ana maye gurbinsu da sababbi koyaushe. Duk da haka, yayin da muke tsufa, ƙarancin ƙwayoyin halitta masu tasowa suna samuwa, a wani ɓangare saboda ƙwayoyin halitta masu tasowa na yau da kullun suna zama ƙwayoyin halitta masu tasowa. Kwayoyin halitta masu tasowa, waɗanda galibi suna iya haifar da tsufa, ba za su iya samar da sabon ƙashi ba, wanda ke haifar da osteoporosis.

Masu bincike na Ostiraliya sun yi nazarin tasirin NMN akan osteoporosis ta hanyar nazarin osteoblasts na ɗan adam. Domin haifar da tsufa, masu binciken sun fallasa osteoblasts ga wani abu mai hana kumburi da ake kira TNF-⍺. Duk da cewa TNF-⍺ yana hanzarta tsufa, magani da NMN ya rage tsufa da kusan sau 3, kuma sakamakon ya nuna cewa NMN ya rage osteoblasts na tsufa.

Kwayoyin osteoblasts masu lafiya suna samar da sabbin ƙwayoyin ƙashi ta hanyar canza su zuwa ƙwayoyin ƙashi masu girma. Masu binciken sun gano cewa haifar da tsufa tare da TNF-⍺ yana rage yawan ƙwayoyin ƙashi masu girma. Duk da haka, NMN ya ƙara yawan ƙwayoyin ƙashi masu girma, kuma sakamakon ya nuna cewa NMN na iya haɓaka samuwar ƙashi.

Bayan binciken ya tabbatar da cewaNMNMasu binciken sun gwada ko hakan na iya faruwa a cikin halittu masu rai. Don yin wannan, sun cire ƙwai na beraye mata suka karya ƙwai na cinyoyinsu, wanda hakan ya haifar da asarar ƙashi wanda ke da alaƙa da osteoporosis.

Domin gwada tasirin NMN akan osteoporosis, masu binciken sun yi wa beraye allurar NMN 400 mg/kg/rana tsawon watanni 2. An gano cewa beraye masu fama da osteoporosis sun ƙara yawan ƙashi, wanda ke nuna cewa NMN ta sake juye alamun osteoporosis kaɗan. Idan aka haɗa ta da bayanan osteoblast na ɗan adam, wannan yana nufin NMN na iya magance osteoporosis ta hanyar ƙara yawan samuwar ƙashi.

二, Tasirin haɓaka ƙashi na NMN

Sakamakon bincike ya nuna cewaNMNzai iya haɓaka samuwar ƙashi. Da alama yana yin hakan ta hanyoyi da dama, gami da sake farfaɗo da ƙwayoyin ƙashi, waɗanda suke da mahimmanci don samar da ƙashi da NAD+, wanda yake da mahimmanci don samar da ƙashi. Kwayoyin ƙashi suna bambanta zuwa osteoblasts, kuma masu bincike sun nuna cewa NMN kuma na iya farfaɗo da osteoblasts.

Waɗannan binciken sun nuna cewa NMN na iya ƙara yawan samuwar ƙashi ta hanyar inganta lafiyar ƙwayoyin ƙashi da yawa a cikin hanyar samuwar ƙashi. Duk da cewa babu wani sakamakon bincike da ya nuna cewa NMN na iya haɓaka samuwar ƙashi a cikin mutanen da ke fama da cutar osteoporosis, yana yiwuwa NMN na iya hana ci gaban ƙashi da ke faruwa da shekaru.