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Ketoreductase (KRED)
Game da Ketoreductase
Enzymes: Su ne macromolecular nazarin halittu catalysts, mafi yawan enzymes sunadaran gina jiki.
Ketoreductase: Har ila yau ana kiranta "Carbonyl reductase", enzymes ne waɗanda ke haifar da redox mai canzawa tsakanin aldehydes / ketones da barasa, kuma suna buƙatar coenzymes azaman mai watsa H kamar NADH ko NADPH.Akwai manyan nau'ikan KRED guda uku: Short-Chain Dehydrogenase / Reductases (SDRs), Dehydrogenases / Reductases (MDRs), da Aldo-KetoReductases (AKRs).Ayyukan catalytic na uku suna kama da juna, amma tsari da kaddarorin sun bambanta sosai.
Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Transaminase (ATA)
Game da transaminase
ATA daga SyncoZymes: Akwai nau'ikan samfuran enzyme na ATA guda 66 (Lambar kamar ES-ATA-101~ES-ATA-166) wanda SyncoZymes ya haɓaka.SZ-ATA kayan aiki ne mai amfani don ƙaddamar da regio- da stereoselective kira na chiral amines, amino acid da abubuwan da suka samo asali daga nau'ikan aliphatic da ketoacids aromatic, aldehydes, ketones da ketoses.
Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Nitrilase (NIT)
Game da Nitrilase
ES-NITs: Kai tsaye canza ƙungiyar cyanide zuwa ƙungiyar carboxyl, don shirya acid carboxylic, wanda ake amfani da shi sosai a magani, kariyar muhalli, masana'antar sinadarai, ƙari na abinci, yadi, samar da noma da sauran fannoni.
Akwai nau'ikan samfuran Nitrilase (NIT) iri 40 (Lambar kamar ES-NIT-101~ES-NIT-140) wanda SyncoZymes ya haɓaka.ES-NIT kayan aiki ne mai amfani don haɓaka haɗakar acid carboxylic na chiral ta hanyar regio- da stereoselective hydrolysis na kewayon aliphatic da nitriles aromatic.Nau'in amsawar catalytic:
Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Nitrile hydratase (NHT)
Game da ES-NHTs
ES-NHTs: nau'in metalloenzyme, wanda ke ba da izinin nitriles a cikin daidaitaccen amide na farko.Ana amfani da su sosai ba kawai don haɗin amino acid, amides, acid carboxylic acid da abubuwan da suka samo asali ba, har ma don shirye-shiryen magungunan chiral.Akwai nau'ikan nitrile hydratases guda 24 waɗanda SyncoZymes suka haɓaka (Lambar kamar ES-NHT-101-ES-NHT-124).
Nau'in amsawar catalytic:
Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Amidase (AMD)
AMD daga SyncoZymes: Akwai nau'ikan samfuran enzyme AMD iri 19 (Lambar kamar ES-AMD-101~ES-AMD-119) wanda SyncoZymes ya haɓaka.SZ-AMD kayan aiki ne mai amfani don ƙaddamar da regio- da stereoselective kira na chiral carboxylic acid da abubuwan da suka samo asali daga nau'ikan aliphatic da aromatic amides.
Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Ene reductase (ERED)
Game da ene reductase
ES-EREDs: Yana cikin dangin tsohuwar enzymes rawaya waɗanda ke zaɓin rage C = C a cikin α, β - mahadi marasa ƙarfi tare da ƙungiyoyi masu ɗaukar lantarki.Ana amfani da su sosai a cikin nazarin abubuwan da suka samo asali na amino acid, abubuwan bioactive, masu tsaka-tsakin magunguna, kayan yaji da tubalan chiral.
Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Oxynitrilases (HNL)
Game da oxynitrilases
ES-HNLs: Wani nau'in enzyme na aji wanda ke ba da damar ƙara HCN zuwa aldehydes (ketones) don samun nau'in cyanide na nau'in R ko S, wanda za'a iya canzawa cikin sauƙi zuwa nau'ikan magunguna ko tsaka-tsakin magunguna ta hanyar sinadarai.
Akwai nau'ikan samfuran oxynitrilase guda 29 (Lambar kamar ES-HNL-101-ES-HNL-129) wanda SyncoZymes ya haɓaka.SZ-HNL kayan aiki ne mai amfani ga regio- da stereo-zabi kira na (R) -cyanohydrins ko (S) -cyanohydrins daga nau'ikan aromatic, aliphatic da heterocyclic aldehydes ko ma ketones.
Nau'in amsawar catalytic:
Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Nitro reductase (NTR)
Game da nitro reductase
ES-NTRs: Su ne flavoenzymes waɗanda ke haifar da raguwar NAD (P) H na dogara ga ƙungiyoyin nitro akan mahaɗan nitroaromatic da nitroheterocyclic zuwa hydroxylamino da/ko abubuwan amino.Ana amfani da su ko'ina a cikin kwayoyin halitta na aromatic hydroxylamine da aromatic amine, ƙari far, gano nazarin halittu da kuma lalatar muhalli gurbatawa.Akwai nau'ikan samfuran Nitro reductase (NTR) iri 12 (Lambar kamar ES-NTR-101~ES-NTR-112) wanda SyncoZymes ya haɓaka.
Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERAs: Za su iya haɓaka haɓakar stereosective ƙari na ketones masu bayarwa zuwa aldehydes mai karɓa.Bugu da ƙari, ana iya aiwatar da martani a cikin bayani mai ruwa na tsaka tsaki pH ba tare da matakan kariya na musamman ba.Suna cikin class I aldolase, wanda ke samar da tushe na Shiff a cikin tsarin catalytic.An haɗe maƙallin tare da rukunin amino na rukunin yanar gizo mai aiki don fara karyewa da samuwar haɗin.Bambanci tsakanin DERAs da sauran aldolases shine cewa abubuwan da suke haɓakawa sune aldehydes kuma suna iya jurewa ci gaba da gurɓacewar aldehydes.
Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Bayanin CYP
ES-CYPs: Wani aji na redox enzymes tare da mercaptan-heme a matsayin cibiyar aiki don haɓaka iskar oxygen.Su ne m oxygenases kuma yana buƙatar heme don kunna oxygen.
Cytochrome P450 monooxygenase catalyze da hadawan abu da iskar shaka, epioxidation da hydroxylation na alkyl, hydroxylation da hadawan abu da iskar shaka na ammonia, hadawan abu da iskar shaka na sulfur, dealkylation (oxygen, sulfur, ammonia), oxidative dehydrogenation, deamination da dehalogenation.
Akwai nau'ikan samfuran cytochrome P450 monooxygenase (Lambar kamar ES-CYP-101-ES-CYP-108) wanda SyncoZymes ya haɓaka.Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Alcohol oxidase (AOX)
Game da barasa oxidase
ES-AOXs: Waɗannan enzymes suna iya haifar da iskar shaka na fatty alcohols ko aryl-alcohols don samar da aldehydes.Suna amfani da iskar oxygen ta kwayoyin halitta amma ba sa buƙatar wani cofactor na waje, da kuma samar da hydrogen peroxide.
Akwai nau'ikan samfuran barasa oxidases guda 6 (Lambar kamar ES-AOX-101~ES-AOX-106) wanda SyncoZymes ya haɓaka.ES-AOX101 da ES-AOX102 sun fi son maye gurbin barasa aliphatic, ES-AOX103~ ES-AOX105 sun fi son maye gurbin barasa, kuma ES-AOX106 shine cholesterol oxidase.SZ-AOX kayan aiki ne mai amfani don ƙaddamar da iskar shaka na barasa mai kitse ko aryl-alcohols don samar da aldehydes.
Nau'in amsawar catalytic:
Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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D-Amino acid dehydrogenase (D-AADH)
Game da D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): wani enzyme wanda zai iya rage 2-keto acid zuwa D-amino acid daidai.Halin yana buƙatar NADP (H) da mai ba da gudummawar ammonia na inorganic (kamar ammonia ko ammonium ion).Akwai nau'ikan D-amino acid dehydrogenases guda 17 (Lambar kamar ES-DAADH-101~ ES-DAADH-117) wanda SyncoZymes ya haɓaka.
Nau'in amsawar catalytic:
Wayar hannu/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
