Fibrosis na hanji da radiation ke haifarwa matsala ce da ta zama ruwan dare gama gari ga waɗanda suka daɗe suna rayuwa bayan tiyatar radiation ta ciki da ƙashin ƙugu. A halin yanzu, babu wata hanyar da ake da ita a asibiti don magance fibrosis na hanji da radiation ke haifarwa. Bincike ya nuna cewa nicotinamide mononucleotide (NMN) yana da ikon daidaita flora na hanji. Flora na hanji wani abu ne da ba a saba gani ba a cikin hanjin ɗan adam, wanda zai iya haɗa nau'ikan abubuwan gina jiki iri-iri da ake buƙata don girma da ci gaban ɗan adam. Da zarar flora na hanji ya lalace, zai haifar da cututtuka iri-iri.
Kwanan nan, Kwalejin Kimiyyar Lafiya ta China da Kwalejin Lafiya ta Peking Union sun buga sakamakon bincike a cikin mujallar International Journal of Radiation Biology, wanda ya nuna cewa NMN na iya rage fibrosis na hanji da radiation ke haifarwa ta hanyar daidaita flora na hanji.
Da farko, ƙungiyar binciken ta raba beraye zuwa ƙungiyar kulawa, ƙungiyar NMN, ƙungiyar IR da ƙungiyar NMNIR, sannan ta ba da hasken ciki na Gy guda 15 ga ƙungiyar IR da ƙungiyar NMNIR. A halin yanzu, an ba da ƙarin NMN ga ƙungiyar NMN da ƙungiyar NMNIR a kowace rana na 300mg/kg. Bayan shan sa na wani lokaci, ta hanyar gano najasar beraye, microflora na hanji da alamun ƙwayoyin hanji, sakamakon kwatantawa ya nuna cewa:
1. NMN na iya gyara abun da ke ciki da aikin flora na hanji wanda radiation ke damun sa.
Ta hanyar kwatanta gano ƙwayoyin hanji tsakanin rukunin IR da rukunin NMNIR, an gano cewa beraye na rukunin IR sun ƙara yawan ƙwayoyin hanji masu cutarwa, kamar Lactobacillus du, Bacillus faecalis, da sauransu. Abin mamaki, beraye na rukunin NMNIR sun canza bambancin ƙwayoyin hanji kuma sun ƙara yawan ƙwayoyin hanji masu amfani, kamar ƙwayoyin cuta na AKK, ta hanyar ƙara NMN. Gwaje-gwaje sun nuna cewa NMN na iya gyara abun da ke ciki da aikin ƙwayoyin hanji wanda ba shi da daidaito saboda radiation.
2. NMN yana rage fibrosis na hanji wanda radiation ke haifarwa
Matsayin aSMA (Mai Alaƙa da Fibrosis) a cikin beraye da aka fallasa ga radiation ya ƙaru sosai. Bayan ƙarin NMN, ba kawai matakin alamar aSMA ya ragu sosai ba, har ma da sinadarin kumburi na TGF-b wanda ke haɓaka fibrosis na hanji ya ragu sosai, wanda ke nuna cewa ƙarin NMN na iya rage fibrosis na hanji da radiation ke haifarwa.
(Hoto na 1. Maganin NMN yana rage fibrosis na hanji wanda radiation ke haifarwa)
A bayan yawaitar kayayyakin lantarki, hasken rana yana da tasiri mai yawa akan aikin mutane da rayuwar su, musamman akan flora na hanji na dogon lokaci. NMN yana da ƙarfi wajen kare lafiyar hanji. Wannan tasirin ba wai kawai yana faruwa ne ta hanyar abu ɗaya ko wata hanya ba, har ma ta hanyar daidaita tsarin rarraba flora don haɓaka kwanciyar hankali na aikin hanji daga kusurwoyi da alkibla daban-daban, wanda kuma yana ba da muhimmiyar ma'ana ga fa'idodi daban-daban na NMN.
Nassoshi:
Xiaotong Zhao, Kaihua Ji, Manman Zhang, Hao Huang, Feng Wang, Yang Liu & Qiang Liu (2022)
Lokacin Saƙo: Disamba-08-2022