β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd. ita ce babbar mai ƙera kuma mai samar da β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS:53-59-8) da inganci mai kyau. Za mu iya samar da COA, isarwa a duk duniya, ƙanana da adadi mai yawa da ake da su. Idan kuna sha'awar wannan samfurin, da fatan za a aiko mana da cikakken bayani wanda ya haɗa da lambar CAS, sunan samfurin, da adadinsa. Da fatan za a tuntuɓe mu:lchen@syncozymes.com
| Sunan Sinadarai | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Ma'ana iri ɗaya | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Lambar CAS | 53-59-8 |
| Nauyin kwayoyin halitta | 743.41 |
| Tsarin Kwayoyin Halitta | C21H28N7O17P3 |
| Lambar EINECS | 200-178-1 |
| zafin ajiya. | A ajiye a wuri mai duhu, yanayi mara motsi, A adana a cikin injin daskarewa, ƙasa da -20°C |
| narkewa | H2O: 50 mg/mL, bayyananne, ɗan rawaya |
| pka | pKa1 3.9; pKa2 6.1(a 25℃) |
| λmax | 260nm (haske) |
| Merck | 14,6348 |
| Tsarin Rijistar Magungunan EPA | Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester tare da 3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, gishirin ciki (53-59-8) |
| Kayan Gwaji | Bayani dalla-dalla |
| Bayyanar | Foda fari zuwa rawaya |
| Narkewa | 200mg/ml a cikin ruwa |
| ƙimar pH (100mg/ml) | 5.0~7.0 |
| Binciken Hasken UV εat 260 nm da pH 7.5 | (18±1.0) × 10³L/mol/cm |
| Abun ciki (ta hanyar nazarin enzymatic tare da G6PDH a pH 7.5, ta amfani da spectrophotometer, abs.340nm, bisa tushen ruwa) | ≥90.0% |
| Tsarkaka (ta hanyar HPLC, %area) | ≥95.0% |
| Yawan ruwa (ta KF) | ≤5% |
Kunshin:Kwalba, jakar foil ta Aluminum, 25kg/Kwatin Drum, ko kuma bisa ga buƙatar abokin ciniki.
Yanayin Ajiya:A rufe da kyau a cikin duhu, don ajiya na dogon lokaci, a ajiye a zafin jiki na 2-8℃.
NADP wani coenzyme ne, wanda shine sinadari wanda nicotinamide adenine dinucleotide da phosphate molecule suke daurewa ta hanyar ester bond, kuma yana wanzuwa sosai.a duniyar halittu. Halayen sinadarai, tasirin sha, siffar redox, da sauransu suna kama da NAD (Coenzyme I). Ana iya amfani da NADP sosai a cikin halayen halayen.wanda ke haifar da sinadarin hydrogenases daban-daban na barasa, ketoroductases da sauran oxidoreductases. Kamar: ana iya rage shi zuwa NADPH ta hanyar dehydrogenases da yawa kamarkamar 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44). Duk da haka, ba lallai bane ya iya amsawa da abubuwa da yawa.dehydrogenases waɗanda ke amfani da NAD, kuma ba za a iya lalata shi kai tsaye ta hanyar sarkar numfashi ba. Ba kamar NAD ba, yana wanzuwa galibi a cikin ƙarancin yanayi a cikin ƙwayoyin halittar halittu masu amfani da iskar oxygen.
Dangane da amfani da samfurin, ana iya raba shi zuwa matakai masu zuwa: matakin biotransformation, matakin reagent na ganewar asali, matakin abinci na lafiya.
Matsayin Biotransformation: Ana iya amfani da shi don haɗa magungunan matsakaici da APIs, galibi tare da enzymes masu kara kuzari, kamar ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), glucose dehydrogenase (GDH), da sauransu. Jira.
Matsayin reagent na ganewar asali: Tare da nau'ikan enzymes na ganewar asali, azaman kayan asali na kayan aikin ganewar asali.
Matsayin abinci mai lafiya: Amfani da ƙarin abinci na NADP galibi yana cikin tsarin bincike da haɓakawa.
