β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd. shine babban masana'anta kuma mai samar da β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS: 53-59-8) tare da inganci mai inganci.Za mu iya samar da COA, isarwa a duniya, ƙanana da yawa da ake samu.Idan kuna sha'awar wannan samfurin, da fatan za a aiko da cikakken bayani ya haɗa da lambar CAS, sunan samfur, yawa gare mu.Da fatan za a tuntuɓi:lchen@syncozymes.com
Sunan Sinadari | β-Nicotinamide adenine dinucleotide phosphate hydrate |
Makamantu | β-Nicotinamide adenine dinucleotide phosphate hydrate |
Lambar CAS | 53-59-8 |
Nauyin Kwayoyin Halitta | 743.41 |
Tsarin kwayoyin halitta | Saukewa: C21H28N7O17P3 |
EINECS No. | 200-178-1 |
yanayin ajiya. | Ajiye a cikin duhu, yanayi mara kyau, Ajiye a cikin injin daskarewa, ƙasa da -20 ° C |
narkewa | H2O: 50 mg/ml, bayyananne, dan kadan rawaya |
pka | pKa1 3.9;pKa2 6.1 (a 25 ℃) |
max | 260nm (lit.) |
Merck | 14,6348 |
Tsarin Rijistar Abun EPA | Adenosine 5'- (trihydrogen diphosphate), 2'- (dihydrogen phosphate), P'.fwdarw.5'-ester tare da 3- (aminocarbonyl) -1-.beta.-D-ribofuranosylpyridinium, gishiri na ciki (53-59- 8) |
Gwajin Abun | Ƙayyadaddun bayanai |
Bayyanar | Fari zuwa rawaya foda |
Solubility | 200mg/ml a cikin ruwa |
pH darajar (100mg/ml) | 5.0 ~ 7.0 |
UV Spectral Analysis 260 nm da pH 7.5 | (18±1.0)×10³L/mol/cm |
Abun ciki (ta hanyar nazarin enzymatic tare da G6PDH a pH 7.5, ta amfani da spectrophotometer, abs.340nm, akan tushen anhydrous) | ≥90.0% |
Tsarki (na HPLC, % yanki) | ≥95.0% |
Abun ciki na ruwa (na KF) | ≤5% |
Kunshin:Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye tam a cikin duhu, don dogon ajiya a ajiye a 2 ~ 8 ℃.
NADP wani coenzyme ne, wanda wani abu ne wanda nicotinamide adenine dinucleotide da kwayar phosphate ke daure ta hanyar ester bond, kuma ya wanzu a ko'ina.a cikin duniyar halitta.Abubuwan sinadarai, nau'ikan sha, nau'in redox, da sauransu suna kama da NAD (Coenzyme I).Ana iya amfani da NADP ko'ina a cikin martanicatalyzed ta daban-daban barasa dehydrogenases, ketoreductases da sauran oxidoreductases.Kamar: ana iya rage shi zuwa NADPH da yawa dehydrogenases irin sukamar 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44).Duk da haka, ba lallai ba ne ya iya amsawa da mutane da yawadehydrogenases da ke amfani da NAD, kuma ba za a iya sanya shi kai tsaye ta hanyar sarkar numfashi ba.Ba kamar NAD ba, yana wanzuwa galibi a cikin raguwar yanayi a cikin sel na kwayoyin halitta.
Dangane da amfani da samfurin, ana iya raba shi zuwa maki masu zuwa: darajar biotransformation, darajar reagent, ƙimar abinci mai lafiya.
Matsayin biotransformation: Ana iya amfani da shi don haɗin magungunan magunguna da APIs, galibi tare da enzymes masu haɓakawa, kamar ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), glucose dehydrogenase (GDH), da dai sauransu Jira.
Matsayin bincike na reagent: Tare da nau'ikan enzymes na bincike iri-iri, azaman albarkatun kayan aikin bincike.
Matsayin abinci na lafiya: Aikace-aikacen ƙarin kayan abinci na NADP galibi yana cikin bincike da tsarin haɓakawa.