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Oxynitrilases (HNL)
Game da oxynitrilases
ES-HNLs: Wani enzyme na aji wanda ke haɓaka ƙara HCN zuwa aldehydes (ketones) don samun nau'in R ko S cyanide alcohols, waɗanda za a iya canza su cikin sauƙi zuwa nau'ikan magunguna ko tsaka-tsakin magunguna ta hanyar sinadarai.
Akwai nau'ikan samfuran oxynitrilase guda 29 (Lambar kamar ES-HNL-101～ES-HNL-129) waɗanda SyncoZymes suka ƙirƙira. SZ-HNL kayan aiki ne mai amfani don haɗa (R)-cyanohydrins ko (S)-cyanohydrins na yankuna da stereo-selective daga nau'ikan aldehydes masu ƙanshi, aliphatic da heterocyclic ko ma ketones.
Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Nitro reductase (NTR)
Game da nitro reductase
ES-NTRs: Flavoenzymes ne waɗanda ke haɓaka rage rukunin nitro na NAD(P)H-dogara da su akan mahaɗan nitroaromatic da nitroheterocyclic zuwa hydroxylamino da/ko abubuwan da suka samo asali daga amino. Ana amfani da su sosai a cikin haɗakar hydroxylamine na halitta da amine na aromatic, maganin ciwon daji, gano halittu da kuma lalata gurɓatattun muhalli. Akwai nau'ikan samfuran Nitro reductase (NTR) guda 12 (Lambar kamar ES-NTR-101~ES-NTR-112) waɗanda SyncoZymes suka ƙirƙira.
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERAs: Yana iya haɓaka ƙara ketones masu bayarwa zuwa aldehydes masu karɓa yadda ya kamata. Bugu da ƙari, ana iya aiwatar da amsawar a cikin ruwan pH mai tsaka tsaki ba tare da matakan kariya na musamman ba. Suna cikin aji na I aldolase, wanda ke samar da tushen Shiff a cikin tsarin catalytic. An haɗa substrate ɗin tare da rukunin amino na wurin aiki don fara karyewa da samuwar haɗin gwiwa. Bambanci tsakanin DERAs da sauran aldolases shine cewa substrates ɗin da suke haɓaka sune aldehydes kuma suna iya fuskantar ci gaba da haɗuwa da aldehydes.
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Game da CYP
ES-CYPs: Ajin enzymes na redox tare da mercaptan-heme a matsayin cibiyar aiki don haɓaka canja wurin oxygen. Su ne terminal oxygenases kuma suna buƙatar heme don kunna oxygen.
Cytochrome P450 monooxygenase yana haɓaka oxidation, epoxidation da hydroxylation na alkyl, hydroxylation da oxidation na ammonia, oxidation na sulfur, dealkylation (oxygen, sulfur, ammonia), oxidative dehydrogenation, deamination da dehalogenation.
Akwai nau'ikan samfuran cytochrome P450 monooxygenase guda 8 (Lambar kamar ES-CYP-101～ES-CYP-108) waɗanda SyncoZymes suka ƙirƙira.Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Barasa mai guba (AOX)
Game da barasa oxidase
ES-AOXs: Waɗannan enzymes suna iya haɓaka iskar shaka ta kitse ko aryl-alcohols don samar da aldehydes. Suna amfani da iskar shaka ta kwayoyin halitta amma ba sa buƙatar wani abu da aka ƙara a waje, kuma ana samar da hydrogen peroxide.
Akwai nau'ikan samfuran barasa oxidase guda 6 (Lambar da aka fi sani da ES-AOX-101~ES-AOX-106) waɗanda SyncoZymes suka ƙirƙira. ES-AOX101 da ES-AOX102 sun fi son sinadaran aliphatic, ES-AOX103~ ES-AOX105 sun fi son sinadaran aromatic, kuma ES-AOX106 shine cholesterol oxidase. SZ-AOX kayan aiki ne mai amfani don haɓaka iskar shaka ta fatty alcohols ko aryl-alcohols don samar da aldehydes.
Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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D-Amino acid dehydrogenase (D-AADH)
Game da D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): wani enzyme wanda zai iya rage acid 2-keto zuwa D-amino acid mai dacewa. Wannan amsawar tana buƙatar NADP(H) da mai ba da gudummawar ammonia mara tsari (kamar ammonia ko ammonium ion). Akwai nau'ikan D-amino acid dehydrogenases guda 17 (Lambar kamar ES-DAADH-101~ ES-DAADH-117) waɗanda SyncoZymes suka ƙirƙira.
Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Esterase da Lipase (PLE&CALB)
Game da Esterase&Lipase
ES-PLES: Wani nau'in hydrolases ne da ke haɓaka samuwar da karyewar haɗin ester. Suna iya shiga cikin nau'ikan halayen sinadarai da yawa, kamar esterification, transesterification da hydrolysis. Ana amfani da su sosai a fannoni da yawa kamar sarrafa abinci, masana'antar sinadarai, maganin biomedicine, maganin chiral da maganin muhalli.
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Epoxide hydrolase (EH)
Game da epoxide hydrolase
EH shine ether hydrolase wanda ke haɓaka hydrolysis na stereoselective na epoxides na racemic don samar da epoxides 1, 2-diol da masu aiki a ido, waɗanda za a iya amfani da su don magance chiral na epoxides ko shirya chiral diols. Ana amfani da su sosai a magani da sauran fannoni. Akwai nau'ikan samfuran epoxide hydrolases guda 3 (Lambar kamar ES-EH-101～ES-EH-103) waɗanda SyncoZymes suka haɓaka. ES-EH kayan aiki ne mai amfani don haɓaka haɗakar chiral alcohols ta hanyar hydrolysis na aliphatic da aromatic epoxides.
Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Tsarin dehydrogenase (FDH)
Game da Formate dehydrogenase
ES-FDH (Format dehydrogenase): FDH yana haɓaka rushewar ammonium formate don samar da carbon dioxide da ammonia, kuma yana rage NAD zuwa NADH tare da NAD a matsayin mai karɓar lantarki. Ana amfani da FDH sau da yawa don sake farfaɗo da coenzyme NADH. Akwai nau'ikan samfuran enzyme FDH guda 4 (ES-FDH-101~ES-FDH-104) waɗanda SyncoZymes suka haɓaka, daga cikinsu ES-FDH102 yana da mafi girman aiki kuma shine FDH da aka fi ba da shawarar.
Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Glucose dehydrogenase (GDH)
Bayani game da Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH yana haɓaka rushewar glucose don samar da gluconic acid (lactone), kuma yana rage NAD(P)+ zuwa NAD(P)H, tare da NAD(P)+ a matsayin mai karɓar lantarki. Ana amfani da GDH sau da yawa don sake farfaɗo da coenzyme NAD(P)H a cikin filayen biocatalysis tare da wasu manyan enzyme. Akwai nau'ikan samfuran enzyme GDH guda 10 (ES-GDH-101~ES-GDH-110) waɗanda SyncoZymes suka haɓaka, daga cikinsu ES-GDH110 yana da mafi girman aiki kuma shine GDH da aka fi ba da shawarar.
Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Monoamine oxidase (MAO)
Game da Monoamine oxidase
ES-MAO(Monoamine oxidase): MAO yana haɓaka lalata ƙwayoyin monoamines na oxidative don samar da hydrogen peroxide, ammonia da aldehydes masu dacewa. A cikin tsarin catalytic, oxygen yana da mahimmanci a matsayin oxidant. Akwai nau'ikan samfuran enzyme na MAO guda 6 (Lambar kamar ES-MAO-101～ES-MAO-106) waɗanda SyncoZymes suka ƙirƙira, waɗanda za a iya amfani da su wajen lalata ƙwayoyin monoamine na oxidative.
Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
Game da Lactate dehydrogenase
Akwai nau'in samfurin enzyme na LDH guda ɗaya (Lambar a matsayin ES-LDH) wanda SyncoZymes ya ƙirƙira. LDH na iya haɓaka rage pyruvate zuwa L-lactic acid, ko rage wasu irin α-keto acid. A cikin tsarin catalysis, NADH ya zama dole a matsayin mai jigilar hydrogen.
Nau'in amsawar lactate dehydrogenasecatalytic
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
