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Transaldolase (TAL)
Game da Transaldolase
ES-TAL (Transaldolase): galibi yana nufin threonine transaldolases, wanda zai iya haɓaka amsawar haɗakar β-hydroxyphenylalanine tare da threonine da benzaldehyde derivatives. TAL enzyme ne da ya dogara da PLP. Akwai nau'in samfurin TAL enzyme 1 kawai (Lambar kamar ES-TAL101) wanda SyncoZymes ya ƙirƙira, wanda za'a iya amfani da shi don haɗa β-hydroxyphenylalanine da abubuwan da ya samo asali.
Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Ketoreductase (KRED)
Game da Ketoreductase
Enzymes: Su ne macromolecular biostimulators, yawancin enzymes sunadarai ne.
Ketoreductase: Wanda kuma ake kira "Carbonyl reductase", enzymes ne da ke haɓaka amsawar redox mai canzawa tsakanin aldehydes / ketones da alcohols, kuma suna buƙatar coenzymes a matsayin mai watsa H kamar NADH ko NADPH. Akwai manyan rukunoni uku na KRED: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), da Aldo-KetoReductases (AKRs). Ayyukan catalytic na uku suna kama da juna, amma tsari da kaddarorin sun bambanta sosai.
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Transaminase (ATA)
Game da transaminase
ATA daga SyncoZymes: Akwai nau'ikan samfuran enzyme na ATA guda 66 (Lambar kamar ES-ATA-101~ES-ATA-166) waɗanda SyncoZymes suka ƙirƙira. SZ-ATA kayan aiki ne mai amfani don haɓaka haɗakar amine na chiral, amino acid da abubuwan da suka samo asali daga nau'ikan ketoacids na aliphatic da aromatic, aldehydes, ketones da ketoses.
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Nitrilase (NIT)
Game da Nitrilase
ES-NITs: Yana canza rukunin cyanide kai tsaye zuwa rukunin carboxyl, don shirya sinadarin carboxylic acid, wanda ake amfani da shi sosai a fannin magani, kare muhalli, masana'antar sinadarai, ƙarin abinci, yadi, samar da aikin gona da sauran fannoni.
Akwai nau'ikan samfuran Nitrilase (NIT) guda 40 (Lambar a matsayin ES-NIT-101~ES-NIT-140) waɗanda SyncoZymes suka ƙirƙira. ES-NIT kayan aiki ne mai amfani don haɓaka haɗakar chiral carboxylic acid ta hanyar hydrolysis na regio- da stereoselective na nitriles iri-iri na aliphatic da aromatic.Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Nitrile hydratase (NHT)
Game da ES-NHTs
ES-NHTs: wani nau'in metalloenzyme ne, wanda ke sanya nitriles cikin sinadarin amide mai kama da juna. Ana amfani da su sosai ba wai kawai don haɗa amino acid, amides, carboxylic acid da abubuwan da suka samo asali ba, har ma don shirya magungunan chiral. Akwai nau'ikan nitrile hydratases guda 24 da SyncoZymes ya samar (Lambar da aka samar a matsayin ES-NHT-101～ES-NHT-124).
Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Amidase (AMD)
AMD daga SyncoZymes: Akwai nau'ikan samfuran enzyme na AMD guda 19 (Lambar kamar ES-AMD-101~ES-AMD-119) waɗanda SyncoZymes suka ƙirƙira. SZ-AMD kayan aiki ne mai amfani don haɓaka haɗakar sinadarai na chiral carboxylic acid da abubuwan da suka samo asali daga nau'ikan aliphatic da aromatic amides.
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Ene reductase (ERED)
Game da ene reductase
ES-EREDs: Suna cikin dangin tsoffin enzymes masu launin rawaya waɗanda ke rage C=C a cikin mahaɗan α, β waɗanda ba su cika ba tare da ƙungiyoyin shaye-shayen electron. Ana amfani da su sosai a cikin nazarin abubuwan da suka samo asali daga amino acid, abubuwan da ke aiki a cikin halitta, abubuwan da ke cikin magunguna, kayan ƙanshi da kuma tubalan chiral.
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Oxynitrilases (HNL)
Game da oxynitrilases
ES-HNLs: Wani enzyme na aji wanda ke haɓaka ƙara HCN zuwa aldehydes (ketones) don samun nau'in R ko S cyanide alcohols, waɗanda za a iya canza su cikin sauƙi zuwa nau'ikan magunguna ko tsaka-tsakin magunguna ta hanyar sinadarai.
Akwai nau'ikan samfuran oxynitrilase guda 29 (Lambar kamar ES-HNL-101～ES-HNL-129) waɗanda SyncoZymes suka ƙirƙira. SZ-HNL kayan aiki ne mai amfani don haɗa (R)-cyanohydrins ko (S)-cyanohydrins na yankuna da stereo-selective daga nau'ikan aldehydes masu ƙanshi, aliphatic da heterocyclic ko ma ketones.
Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Nitro reductase (NTR)
Game da nitro reductase
ES-NTRs: Flavoenzymes ne waɗanda ke haɓaka rage rukunin nitro na NAD(P)H-dogara da su akan mahaɗan nitroaromatic da nitroheterocyclic zuwa hydroxylamino da/ko abubuwan da suka samo asali daga amino. Ana amfani da su sosai a cikin haɗakar hydroxylamine na halitta da amine na aromatic, maganin ciwon daji, gano halittu da kuma lalata gurɓatattun muhalli. Akwai nau'ikan samfuran Nitro reductase (NTR) guda 12 (Lambar kamar ES-NTR-101~ES-NTR-112) waɗanda SyncoZymes suka ƙirƙira.
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERAs: Yana iya haɓaka ƙara ketones masu bayarwa zuwa aldehydes masu karɓa yadda ya kamata. Bugu da ƙari, ana iya aiwatar da amsawar a cikin ruwan pH mai tsaka tsaki ba tare da matakan kariya na musamman ba. Suna cikin aji na I aldolase, wanda ke samar da tushen Shiff a cikin tsarin catalytic. An haɗa substrate ɗin tare da rukunin amino na wurin aiki don fara karyewa da samuwar haɗin gwiwa. Bambanci tsakanin DERAs da sauran aldolases shine cewa substrates ɗin da suke haɓaka sune aldehydes kuma suna iya fuskantar ci gaba da haɗuwa da aldehydes.
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Game da CYP
ES-CYPs: Ajin enzymes na redox tare da mercaptan-heme a matsayin cibiyar aiki don haɓaka canja wurin oxygen. Su ne terminal oxygenases kuma suna buƙatar heme don kunna oxygen.
Cytochrome P450 monooxygenase yana haɓaka oxidation, epoxidation da hydroxylation na alkyl, hydroxylation da oxidation na ammonia, oxidation na sulfur, dealkylation (oxygen, sulfur, ammonia), oxidative dehydrogenation, deamination da dehalogenation.
Akwai nau'ikan samfuran cytochrome P450 monooxygenase guda 8 (Lambar kamar ES-CYP-101～ES-CYP-108) waɗanda SyncoZymes suka ƙirƙira.Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
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Barasa mai guba (AOX)
Game da barasa oxidase
ES-AOXs: Waɗannan enzymes suna iya haɓaka iskar shaka ta kitse ko aryl-alcohols don samar da aldehydes. Suna amfani da iskar shaka ta kwayoyin halitta amma ba sa buƙatar wani abu da aka ƙara a waje, kuma ana samar da hydrogen peroxide.
Akwai nau'ikan samfuran barasa oxidase guda 6 (Lambar da aka fi sani da ES-AOX-101~ES-AOX-106) waɗanda SyncoZymes suka ƙirƙira. ES-AOX101 da ES-AOX102 sun fi son sinadaran aliphatic, ES-AOX103~ ES-AOX105 sun fi son sinadaran aromatic, kuma ES-AOX106 shine cholesterol oxidase. SZ-AOX kayan aiki ne mai amfani don haɓaka iskar shaka ta fatty alcohols ko aryl-alcohols don samar da aldehydes.
Nau'in amsawar catalytic:
Wayar Salula/Wechat/WhatsApp: +86-13681683526
Imel:lchen@syncozymes.com
